@ The Barbara Davis Center for Childhood Diabetes/UCHSC

Publication List

The DAISY study has published multiple works about the study of type 1 diabetes. Many of the articles have summaries that are available online. If you would like a copy of the full text article, please email us.
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009

1995

1. Gianani R, Rabin DU, Verge CF, Yu L, Babu S, Pietropaolo M, Eisenbarth GS. ICA512 autoantibody radioassay. Diabetes 1995; 44:1340-4.
Article Summary

2. Eisenbarth GS, Rewers M. Refining genetic analysis of type I diabetes. J Clin Endocrinol Metab 1995; 80:2564-6.

3. Yu L, Chase HP, Falorni A, Rewers M, Lernmark Ĺ, Eisenbarth GS. Sexual dimorphism in transmission of expression of islet autoantibodies to offspring. Diabetologia 1995; 38:1353-1357.
Article Summary

Return to Top

1996

4. Gianani R, Verge CF, Moromisato-Gianani RI, Yu L, Pugliese A, Eisenbarth GS. Limited loss of tolerance to islet autoantigens in ICA+ first degree relatives of patients with type I diabetes expressing the HLA DQB1*0602 allele. J Autoimmun 1996; 9:423-5.
Article Summary

5. Rewers M, TL Bugawan, JM Norris, A Blair, B Beaty, M Hoffman, RS McDuffie, RF Hamman, G Klingensmith, GS Eisenbarth, H Erlich. Newborn screening for HLA markers associated with IDDM. Diabetologia 1996; 39:807-812.
Article Summary

6. Rewers M, Norris JM, Eisenbarth GS, Erlich HA, beathy B, Klingensmith G, Hoffman M, Yu Liping, Bugawan TL, Blair A, Hamman RF, et al. Beta-cell autoantibodies in infants and toddlers without IDDM relatives. J Autoimmunity 1996; 9:405-10.
Article Summary

7. Yu L, M Rewers, R Gianani, E Kawasaki, Y Zhang, Ch Verge, P Chase, G Klingensmith, H Erlich, J Norris, GS Eisenbarth. Anti-islet autoantibodies develop sequentially rather than simultaneously. J Clin Endocrinol Metabol 1996; 81:4264-67.
Article Summary

8. Norris JM, B Beaty, G Klingensmith, L Yu, M Hoffman, HP Chase, HA Erlich, RF Hamman, GS Eisenbarth, M Rewers. Lack of association between early exposure to cow's milk protein and beta-cell autoimmunity. JAMA 1996; 276:609-14.
Article Summary

Return to Top

1997

9. Graves PM, MA Pallansch, JM Norris, M Rewers. The role of enteroviral infections in the development of IDDM: limitations of current approaches. Diabetes 1997; 46:161-8.
Article Summary

10. Schloot NC, Roep BO, Wegmann D, Yu L, Chase HP, Wang T, Eisebarth GS. Altered immune response to insulin in newly diagnosed compared to insulin-treated diabetic patients and healthy control subjects. Diabetologia 1997; 40:564-72.
Article Summary

11. Schloot NC, Roep BO, Wegmann DR, Yu L, Wang TB, Eisenbarth GS. T cell reactivity to GAD65 peptide sequences shared with coxsackie virus protein in recent-onset IDDM patients and control subjects. Diabetologia 1997; 40:332-8.
Article Summary

12. Rewers M, GJ Klingensmith. Prevention of type 1 diabetes. Diabetes Spectrum 1997; 10:282-91.

13. Kawasaki, E., Yu, L., Gianani, R., Verge, C. F., Babu, S., Bonifacio, E., and Eisenbarth, G. S. Evaluation of Islet Cell Antigen (ICA) 512/IA-2 autoantibody radioassays using overlapping ICA512/IA-2 constructs. J Clin Endocrinol Metab. 1997; 82(2):375-80.
Article Summary

Return to Top

1998

14. Ricalton NS, Roberton C, Norris JM, Rewers M, Hamman RF, Kotzin BL. Prevalence of CD8+ T cell expansions in relation to age in healthy individuals. J Gerontol A Biol Sci Med Sci 1998; 53:B196-203.
Article Summary

15. Kawasaki E, L Yu, M Rewers, JC Hutton, GS Eisenbarth. Definition of multiple ICA512/phogrin autoantibody epitopes and detection of intramolecular epitope spreading in relatives of patients with type 1 diabetes. Diabetes 1998; 47:733-42.
Article Summary

Return to Top

1999

16. Flanders G, Graves P, Rewers M. Prevention of type 1 diabetes: From laboratory to public health. J Autoimmunity 1999; 29:235-46.
Article Summary

17. Redondo MJ, Rewers M, Yu L, Garg S, Pilcher CC, Elliott RB, Eisenbarth GS. Genetic determination of islet cell autoimmunity in monozygotic twin, dizygotic twin, and non-twin siblings of patients with type 1 diabetes. BMJ 1999; 318:698-702.
Article Summary

18. Bao F, L Yu, S Babu, T Wang, EJ Hoffenberg, M Rewers, GS Eisenbarth GS. One third of HLA DQ2 homozygous patients with type 1 diabetes express celiac disease associated transglutaminase autoantibodies. J Autoimmunity 1999; 13:143-8.
Article Summary

19. Yu MS, Norris JM, Mitchell CM, Butler-Simon N, Groshek M, Follensbee D, Erlich H, Rewers M, Klingensmith GJ. The impact on maternal parenting stress of receipt of genetic information regarding risk of diabetes in newborns. Am J Med Genet 1999; 86:219-26.
Article Summary

20. Yu L, Brewer KW, Gates S, Wang T, Babu S, Gottlieb PA, Freed B, Rewers M, Erlich HA, Eisenbarth GS. DRB1*04 and DQ Alleles: Expression of 21-Hydroxylase autoantibodies and risk of progression to Addison's Disease. J Clin Endocrinol Metabol 1999; 84:328-35.
Article Summary

21. Redondo M, PA Gottlieb, T Motheral, C Mulgrew, M Rewers, S Babu, E Stephens, DR Wegmann, GS Eisenbarth. Heterophile anti-mouse immunoglobulin antibodies may interfere with cytokine measurements in patients with HLA alleles protective for type 1A diabetes. Diabetes 1999; 48:2166-70.
Article Summary

22. Graves PM, Norris JM, Barriga K, Erlich H, Eisenbarth GS, Rewers M. Lack of association between early childhood immunizations and beta-cell autoimmunity. Diabetes Care 1999; 22:1694-7.
Article Summary

23. Deutsch J., Butler J,. Marsh A., Ross C., Norris J. Rapid mass spectrometric analysis for ascorbate and related organic acids in small volumes of plasma for use in pediatric subjects. Journal of Chromatography B 1999; 726:79-84.
Article Summary

Return to Top

2000

24. Yu L, Robles DT, Abiru N, Kaur P, Rewers M, Kelemen K, Eisenbarth GS. Early expression of anti-insulin autoantibodies of humans and the NOD mouse: evidence for early determination of subsequent diabetes. PNAS 2000; 97:1701-6.
Article Summary

25. Yu J, L Yu, TL Bugawan, HA Erlich, K Barriga, M Hoffman, M Rewers, GS Eisenbarth. Transient anti-islet autoantibodies: infrequent occurrence and lack of association with "genetic" risk factors. J Clin Endocrinol & Metab 2000; 85:2421-8.
Article Summary

26. Park YS, Kawasaki E, Kelemen K, Yu L, Schiller MR, Rewers M, Eisenbarth GS, Hutton JC. Humoral autoreactivity to an alternatively spliced variant of ICA512/IA-2 in type 1 diabetes. Diabetologia 2000; 43:1293-301.
Article Summary

27. Abiru N, Yu L, Redondo MJ, Eisenbarth GS. Modification of the environment is not the most efficient way to prevent type 1 diabetes. Diabetes Technology and Therapeutics 2000; 2:609-16.
Article Summary

28. Hoffenberg EJ, Bao F, Eisenbarth GS, Uhlhorn C, Haas J, Sokol RJ, Rewers M. Transglutaminase antibodies in children with a genetic risk for celiac disease. J Pediatr 2000; 137:356-60.
Article Summary

Return to Top

2001

29. Maniatis AK, Yu L, Miao D, Nelson K, Eisenbarth GS. Rapid Assays for Detection of Anti-islet Autoantibodies: Implications for Organ Donor Screening. J Autoimmun 2001; 16:71-6.
Article Summary

30. Redondo MJ, Yu L, Hawa M, Mackenzie T, Pyke DA, Eisenbarth GS. Heterogeneity of type I diabetes: analysis of monozygotic twins in Great Britain and the United States. Diabetologia 2001; 44:354-62.
Article Summary

Return to Top

2002

31. Robles DT, Eisenbarth GS, Wang T, Erlich HA, Bugawan TL, Babu SR, Barriga K, Norris JM, Hoffman M, Klingensmith G, Yu L, Rewers M. Identification of Children with Early Onset and High Incidence of Anti-islet Autoantibodies. Clin Immun 2002; 102:217-24.
Article Summary

Return to Top

2003

32. Graves PM, Rotbart HA, Nix WA, Pallansch MA, Erlich HA, Norris JM, Hoffman M, Eisenbarth GS, Rewers M. Prospective study of enteroviral infections and development of beta-cell autoimmunity: Diabetes autoimmunity study in the young (DAISY). Diabetes Research and Clinical Practice 2003; 59:51-61.
Article Summary

33. Norris JM, Barriga K, Klingensmith G, Hoffman M, Eisenbarth GS, Erlich HA, Rewers M. Timing of Initial Cereal Exposure in Infancy and Risk of Islet Autoimmunity. JAMA 2003; 290(13): 1713-1720.
Article Summary

34. Stene LC, Barriga K, Norris JM, Hoffman M, Klingensmith G, Erlich HA, Eisenbarth GS, Rewers M. Symptoms of Common Maternal Infections in Pregnancy and Risk of Islet Autoimmunity in Early Childhood. Diabetes Care 2003; 26(11): 3136-3141.
Article Summary

35. Fronczak CM, Barón AE, Chase HP, Ross C, Brady HL, Hoffman M, Eisenbarth GS, Rewers M, Norris JM. In utero dietary exposures and risk of islet autoimmunity in children. Diabetes Care 2003; (12):3237-42.
Article Summary

Return to Top

2004

36. Stanley HM, Norris JM, Barriga K, Hoffman M, Yu L, Miao D, Erlich HA, Eisenbarth GS, Rewers M. Is presence of islet autoantibodies at birth associated with development of persistent islet autoimmunity? The Diabetes Autoimmunity Study in the Young (DAISY). Diabetes Care 2004; 27(2): 497-502.
Article Summary

37. Barker JM, Goehrig SH, Barriga K, Hoffman M, Slover R, Eisenbarth G, Norris J, Klingensmith GJ, Rewers M. Clinical characteristics of children diagnosed with type 1 diabetes through intensive screening and follow-up. Diabetes Care 2004; 27(6): 1399-1404.
Article Summary

38. Stene LC, Barriga K, Norris JM, Hoffman M, Erlich HA, Eisenbarth GS, McDuffie RS, Rewers M. Perinatal factors and development of islet autoimmunity in early childhood. The Diabetes Autoimmunity Study in the Young (DAISY). Am J Epidemiol 2004; 160(1): 3-10.
Article Summary

39. Barker JM, Barriga KJ, Yu L, Miao D, Erlich HA, Norris JM, Eisenbarth GS, Rewers M. Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY). J Clin Endocrinol Metab 2004;89(8):3896-902
Article Summary

40. Chase P, Cooper S, Osberg I, Stene L, Barriga K, Norris J, Eisenbarth G, Rewers M. Elevated C-Reactive Protein Levels in the Development of Type 1 Diabetes. Diabetes 2004; 53: 2569-2573.
Article Summary

41. Cruz T, Valdes A, Santiago A, Frazer de Llado T, Raffel L, Zeidler A, Rotter J, Erlich H, Rewers M, Bugawan T, Noble J. DPB1 Alleles are associated with type 1 diabetes susceptibility in multiple ethnic groups. Diabetes 2004; 53: 2158-2163.
Article Summary

42. Park Y, Kim S, Park S, Kim T, Yu L, Rewers M, Eisenbarth GS. Differential Expression of Nonislet Autoimmunity: Comparison of Korean and U.S. Patients with Type 1 Diabetes. Ann N Y Acad Sci 2004; 1037:69-73.
Article Summary

43. Rewers M, Zimmet P. The rising tide of childhood type 1 diabetes--what is the elusive environmental trigger? Lancet 2004; 364(9446):1645-7.
Article Summary

44. Hoffenberg EJ, Emery LM, Barriga KJ, Bao F, Taylor J, Eisenbarth GS, Haas JE, Sokol RJ, Taki I, Norris JM, Rewers M. Clinical Features of Children With Screening-Identified Evidence of Celiac Disease. Pediatrics 2004;113(5):1254-9.
Article Summary

45. Rewers M, Liu E, Simmons J, Redondo MJ, Hoffenberg EJ. Celiac disease associated with type 1 diabetes mellitus. Endocrinol Metab Clin North Am. 2004; 33(1):197-214.
Article Summary

Return to Top

2005

46. Steck AK, Barriga KJ, Emery LM, Fiallo-Scharer RV, Gottlieb PA, Rewers MJ. Secondary attack rate of type 1 diabetes in Colorado families. Diabetes Care 2005;28(2):296-300.
Article Summary

47. Ferucci ED, Majka DS, Parrish LA, Moroldo MB, Ryan M, Passo M, Thompson SD, Deane KD, Rewers M, Arend WP, Glass DN, Norris JM, Holers VM. Antibodies against cyclic citrullinated peptide are associated with HLA-DR4 in simplex and multiplex polyarticular-onset juvenile rheumatoid arthritis. Arthritis Rheum 2005;52(1):239-46.
Article Summary

48. Norris JM, Barriga K, Hoffenberg E, Taki I, Miao DM, Haas JE, Emery LM, Sokol RJ, Erlich HA, Eisenbarth GS, Rewers M. Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease. JAMA 2005;293(19):2343-51.
Article Summary

49. Steck AK, Bugawan TL, Valdes AM, Emery LM, Blair A, Norris JM, Redondo MJ, Babu SR, Erlich HA, Eisenbarth GS, Rewers MJ. Association of Non-HLA Genes With Type 1 Diabetes Autoimmunity. Diabetes 2005; 54(8):2482-6.
Article Summary

50. Ide A, Babu SR, Robles DT, Wang T, Erlich HA, Bugawan TL, Rewers M, Fain PR, Eisenbarth GS."Extended" A1, B8, DR3 haplotype shows remarkable linkage disequilibrium but is similar to nonextended haplotypes in terms of diabetes risk. Diabetes 2005; 54(6):1879-83.
Article Summary

51. Emery LM, Babu S, Bugawan TL, Norris JM, Erlich HA, Eisenbarth GS, Rewers M. Newborn HLA-DR,DQ genotype screening: age- and ethnicity-specific type 1 diabetes risk estimates. Pediatric Diabetes 2005; 6:136-144.
Article Summary

52. Ide A, Babu SR, Robles DT, Wang T, Erlich HA, Bugawan TL, Rewers M, Fain PR, Eisenbarth GS. Homozygosity for premature stop codon of the MHC class 1 chain-related gene A (MIC-A) is associated with early activation of islet autoimmunity of DR3/4-DQ2/8 High Risk DAISY Relatives. Journal of Clinical Immunology 2005; 25(4):303-8.
Article Summary

53. Liu E, Li M, Bao F, Miao D, Rewers M, Eisenbarth GS, Hoffenberg EJ. A Need for Quantitative Assessment of Transglutaminase Autoantibodies in Screening-Identified Children for Celiac Disease. The Journal of Pediatrics 2005; 146(4):494-9.
Article Summary

54. Aly TA, Ide A, Humphrey K, Barker JM, Steck A, Erlich HA, Yu L, Miao D, Redondo MJ, McFann K, Roberts CM, Babu SR, Norris JM, Eisenbarth GS, Rewers MJ. Genetic prediction of autoimmunity: Initial oligogenic prediction of anti-islet autoimmunity amongst DR3/DR4-DQ8 relatives of patients with type 1A diabetes. J Autoimmun. 2005; 25 Suppl:40-5.
Article Summary

Return to Top

2006

55. Aly T, Eller E, Ide A, Gowan K, Babu S, Erlich H, Rewers M, Eisenbarth G, Fain P. Multi-SNP analysis of MHC region: remarkable conservation of HLA-A1-B8-DR3 haplotype. Diabetes 2006; 55(5):1265-9.
Article Summary

56. Poole J, Barriga K, Leung D, Hoffman M, Eisenbarth G, Rewers M, Norris J. Timing of initial exposure to cereal grains and the risk of wheat allergy. Pediatrics 2006; 117(6): 2175-82.
Article Summary

57. Aly T, Ide A, Jahromi M, Barker J, Fernando M, Babu S, Yu L, Miao D, Erlich H, Fain P, Barriga K, Norris J, Rewers M, Eisenbarth G. Extreme genetic risk for type 1A diabetes. Proceedings of the National Academy of Sciences U S A. 2006 103 (38): 14074-14079.
Article Summary

58. Stene L, Honeyman M, Hoffenberg E, Haas J, Sokol R, Emery L, Taki I, Norris J, Erlich H, Eisenbarth G, Rewers M. Rotavirus Infection Frequency and Risk of Celiac Disease Autoimmunity in Early Childhood: A Longitudinal Study. Am J Gastroenterol. 2006; 101(10): 2333-40.
Article Summary

59. Stene L, Barriga K, Hoffman M, Kean J, Klingensmith G, Norris J, Erlich H, Eisenbarth G, Rewers M. Normal but increasing hemoglobin A1C levels predict progression from islet autoimmunity to overt type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY). 2006; 7: 247-253.
Article Summary

60. Steck A, Liu S-Y, McFann K, Barriga K, Babu S, Eisenbarth G, Rewers M, She J-X. Association of the PTPN22/LYP gene with type 1 diabetes. Pediatric Diabetes 2006; 7: 274–278.
Article Summary

Return to Top

2007

61. Bhatia SS, Majka DS, Kittelson JM, Parrish LA, Ferucci ED, Deane KD, Arend WP, Rewers M, Holers VM, Norris JM. Rheumatoid factor seropositivity is inversely associated with oral contraceptive use in women without rheumatoid arthritis. Ann Rheum Dis 2007: 66: 267-269.
Article Summary

62. Young K, Parrish L, Zerbe G, Rewers M, Deane K, Holers M, Norris J. Perinatal and early childhood risk factors associated with rheumatoid factor positivity in a healthy paediatric population. Ann Rheum Dis, 2007; 66: 179 - 183.
Article Summary

63. Brady H, Lamb MM, Sodol RJ, Ross CA, Seifert JA, Rewers MJ, Norris JM. Plasma micronutrients are associated with dietary intake and environmental tobacco smoke exposure in a pediatric population. Public Health Nutr 2007 Jul; 10(7):712-8.
Article Summary

64. Baschal EE, Aly TA, Babu SR, Fernando MS, Yu L, Miao D, Barriga KJ, Norris JM, Noble JA, Erlich HA, Rewers MJ, Eisenbarth GS. HLA-DPB1*0402 protects against type 1A diabetes autoimmunity in the highest risk DR3-DQB1*0201/DR4-DQB1*0302 DAISY population. Diabetes 2007 Sep; 56(9):2405-9.
Article Summary

65. Liu E, Li M, Emery L, Taki I, Barriga K, Tiberti C, Eisenbarth GS, Rewers MJ, Hoffenberg EJ. Natural history of antibodies to deamidated gliadin peptides and transglutaminase in early childhood celiac disease. Journal of Pediatric Gastroenterology and Nutrition 2007 Sep; 45(3):293-300.
Article Summary

66. Norris JM, Yin X, Lamb MM, Barriga K, Seifert J, Hoffman M, Orton HD, Baron AE, Clare-Salzler M, Chase HP, Szabo NJ, Erlich H, Eisenbarth GS, Rewers M. Omega-3 polyunsaturated fatty acid intake and islet autoimmunity in children at increased risk for type 1 diabetes. JAMA 2007 Sep; 298(12):1420-8.
Article Summary

67. Wenzlau JM, Juhl K, Yu L, Moua O, Sarkar SA, Gottlieb P, Rewers M, Eisenbarth GS, Jensen J, Davidson HW, Hutton JC. The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes. Proceedings of the National Academy of Sciences (U.S.) 2007 Oct 23; 104(43):17040-5.
Article Summary
Review in Rocky Mountain News

Return to Top

2008

68. Lamb MM, Myers MA, Barriga K, Zimmet PZ, Rewers M, Norris JM. Maternal diet during pregnancy and islet autoimmunity in offspring. Pediatric Diabetes 2008 Apr;9(2):135-41.
Article Summary

69. Lamb MM, Yin X, Barriga K, Hoffman MR, Barón AE, Eisenbarth GS, Rewers M, Norris JM. Dietary glycemic index, development of islet autoimmunity, and subsequent progression to type 1 diabetes in young children. Journal of Clinical Endocrinology & Metabolism 2008 Oct; 9 3(10):3936-42.
Article Summary

70. Aly TA, Baschal EE, Jahromi MM, Fernando MS, Babu SR, Fingerlin TE, Kretowski A, Erlich HA, Fain PR, Rewers MJ, Eisenbarth GS. Analysis of single nucleotide polymorphisms identifies major type 1A diabetes locus telomeric of the major histocompatibility complex. Diabetes 2008 Mar; 57(3):770-6.
Article Summary

71. Barker JM, Triolo TM, Aly TA, Baschal EE, Babu SR, Kretowski A, Rewers MJ, Eisenbarth GS. Two single nucleotide polymorphisms identify the highest-risk diabetes HLA genotype: potential for rapid screening. Diabetes 2008 Nov; 57(11):3152-5.
Article Summary

72. Wenzlau JM, Moua O, Sarkar SA, Yu L, Rewers M, Eisenbarth GS, Davidson HW, Hutton JC. SlC30A8 is a major target of humoral autoimmunity in type 1 diabetes and a predictive marker in prediabetes. Ann N Y Acad Sci. 2008 Dec; 1150:256-9.
Article Summary

Return to Top

2009

73. Li M, Yu L, Tiberti C, Bonamico M, Taki I, Miao D, Murray JA, Rewers MJ, Hoffenberg EJ, Agardh D, Mueller P, Stern M, Bonifacio E. Liu E. A report on the International Transglutaminase Autoantibody Workshop for Celiac Disease. Am J Gastroenterol. 2009 Jan;104(1):154-63.
Article Summary

74. Steck AK, Zhang W, Bugawan TL, Barriga KJ, Blair A, Erlich HA, Eisenbarth GS, Norris JM, Rewers MJ. Do non-HLA genes influence development of persistent islet autoimmunity and type 1 diabetes in children with high-risk HLA-DR,DQ genotypes?Diabetes 2009 Apr; 58(4):1028-33.
Article Summary

75. Lamb MM, Yin X, Zerbe GO, Klingensmith GJ, Dabelea D, Fingerlin TE, Rewers M, Norris JM. Height growth velocity, islet autoimmunity and type 1 diabetes development: the Diabetes Autoimmunity Study in the Young. Diabetologia 2009 Oct; 52(10):2064-71.
Article Summary

76. Simpson M, Mojibian M, Barriga K, Scott FW, Fasano A, Rewers M, Norris JM. An exploration of Glo-3A antibody levels in children at increased risk for type 1 diabetes mellitus. Pediatric Diabetes. 2009 Dec; 10(8):563-72.
Article Summary

77. Lamb MM, Dabelea D, Yin X, Ogden LG, Klingensmith GJ, Rewers M, Norris JM. Early-Life Predictors of Higher Body Mass Index in Healthy Children. Annals of nutrition and metabolism 2009 Nov 27; 56(1):16-22.
Article Summary

Return to Top